Rhabdomyolysis Triggered by Statin Use: A Case Report
Jafrin Sadiq Abdul Razack *
Thumbay University Hospital, Ajman, United Arab Emirates.
Shoaib Shah Ahamed
Thumbay University Hospital, Ajman, United Arab Emirates.
Noel George Cherian
Thumbay University Hospital, Ajman, United Arab Emirates.
Ajmal Sainul
Thumbay University Hospital, Ajman, United Arab Emirates.
Aia Nana
Thumbay University Hospital, Ajman, United Arab Emirates.
Antony Calvin Ossanam
Medical Graduate, Gulf Medical University, Ajman, United Arab Emirates.
*Author to whom correspondence should be addressed.
Abstract
Rhabdomyolysis is a serious condition marked by the rapid breakdown of skeletal muscle, leading to the release of intracellular contents that can cause complications such as acute kidney injury (AKI). Statins are a known, though rare, cause of rhabdomyolysis. We report a case of severe statin-induced rhabdomyolysis in a male patient presenting with AKI and markedly elevated creatine phosphokinase levels. Despite supportive treatment with IV fluids and bicarbonate, he required hemodialysis. Following multiple sessions and continued care, his renal function and symptoms gradually improved. This case highlights the importance of early recognition and intervention in statin-associated rhabdomyolysis to prevent irreversible renal damage.
Keywords: Rhabdomyolysis, skeletal muscle, statin, therapy, acute kidney injury