A Nephrotic Syndrome Induced by Rifampicin
Molenga.M *
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Tchich.H
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Kasangana.B
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
El khayat. S.S
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Mtioui. N
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Zamd.M
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Medkouri. G
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Benghanem.M
Nephrology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
*Author to whom correspondence should be addressed.
Abstract
The aim of this paper is to remind practitioners of this unusual complication of anti-tuberculosis treatment. It is a rare side effect, but it can be a source of chronic disease.
A 20-year-old female patient being treated for lymph node tuberculosis presented with a generalized edematous syndrome one week after starting anti-tuberculosis treatment. She had a history of mental illness and lymph node tuberculosis diagnosed 3 months prior to admission.
The diagnosis of a nephrotic syndrome with minimal glomerular lesions was made based on biological and anatomopathological arguments.
The responsibility of rifampicin was assessed using the French method of imputability for unexpected or toxic effects of drugs.
The patient was managed medically with a satisfactory outcome.
We report a rare but potentially serious side effect associated with rifampicin.
Keywords: Rifampicin, kidney failure, nephrotic syndrome, tuberculosis