Asian Journal of Research in Nephrology

Acute Kidney Injury Due to Wild Mushroom Consumption: Hemodialysis and Ozone therapy Combination a Therapeutic Asset (About One Case)

Séraphin Ahoui *

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Evariste Eteka

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Wylliam Guedjo

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Julien Attinon

Army Training Hospital of Parakou, Parakou, Benin.

Nicanor Houéto

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Djima Hermione N. M.

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Willis Allawenon

Hospital Saint John of God of Tanguiéta, Tanguiéta, Benin.

Tchaou Blaise A.

Training and Research Unit in Nephrology, Faculty of Medicine, University of Parakou, Benin.

Giam Batista Priuli

Hospital Saint John of God of Tanguiéta, Tanguiéta, Benin.

*Author to whom correspondence should be addressed.

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Abstract

Aims: to assess the value of ozone therapy in the management of acute toxic kidney injury due to the ingestion of wild mushrooms.

Case Presentation: This was a prospective case study of a 30-year-old patient who was hospitalized in the nephrology department of the Departmental Teaching Hospital of Borgou (Benin), in November 2021, for acute toxic renal failure following severe intoxication by ingestion of wild mushrooms. His condition required hemodialysis sessions coupled with ozone therapy.                 Three sessions of hemodialysis coupled with ozone therapy were performed, followed by four sessions of isolated ozone therapy in two weeks.  The recovery of renal function was favorable and faster. A rapid clinical improvement was noted as well as a regularization of the paraclinical parameters.

Discussion: Ozone therapy, as an adjuvant treatment, due to its anti-inflammatory, antioxidant and cell growth properties, favored a rapid recovery of the renal function and a clinical improvement of the patient victim of a severe intoxication by ingestion of wild mushrooms. This is the case of a multidisciplinary management of acute toxic renal failure by ingestion of wild mushroom, the management of which was done with hemodialysis associated with ozone therapy, the results being quite interesting.

Conclusion: Ozone therapy in adjuvant treatment could facilitate a rapid recovery of renal function.

Keywords: Acute kidney injury, wild mushrooms, ozone therapy, Benin

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