The Relationship of Chronic Kidney Diseases Stages and Dipstick Proteinuria for Bangladeshi Patients
Published: 2021-10-12
Page: 82-87
Issue: 2021 - Volume 4 [Issue 1]
Mahbuba Yesmin *
Department of Medicine, Enam Medical College and Hospital (EMCH), Savar, Bangladesh.
M. A. Jalil Chowdhury
Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka 1000, Bangladesh.
Afroja Alam
Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka 1000, Bangladesh.
Nirmol Kumar Biswas
National Institute of Cardiovascular Disease (NICVD), Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Background: It is established that proteinuria is associated with kidney dysfunction. The endeavor in this study was to observe whether the degree of dipstick proteinuria was related to the progressive stages of chronic kidney disease (CKD) for Bangladeshi patients.
Methods: This observational study was carried out on a total of 100 patients above 18 years of either sex with chronic kidney disease in the Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Data were collected through semi-structured questionnaire. p-value <0.05 was considered statistically significant. The data were analyzed by SPSS version 25.
Results: The mean age of the study population was 43.26 ±13.07 years with male predominance (63%). Serum creatinine increased with ages. The major symptoms were swelling of face, feet and ankle; nausea, vomiting and loss of appetite; breathlessness, urinary complaints, and also weakness. The causes for CKD were diabetes, hypertension, glomerular disease, systemic Inflammatory disease, previous history of kidney disease, and tubulointerstitial disease. The number of CKD patients in stage 3 was 16%, in stage 4 was 32% and in stage 5 was 52%. The dipstick proteinuria increased significantly with progressive stages of CKD.
Conclusion: The range of proteinuria increased with the progressive stages of CKD.
Keywords: Chronic kidney disease (CKD), proteinuria, glomerular filtration rate (GFR)