Asian Journal of Research in Nephrology

Review Article on Treatment of Nephrotic Syndrome in Pediatrics

Sk. Md. Abbas *

Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, India.

A. Noorjahan

Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, India.

C. Bhargav Reddy

Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, India.

Y. Saivani

Department of Nephrology, Santhiram Medical College and General Hospital, Nandyal, India.

R. E. Ugandhar

Department of Nephrology, Santhiram Medical College and General Hospital, Nandyal, India.

C. Madhusudhan Chetty

Department of Nephrology, Santhiram Medical College and General Hospital, Nandyal, India.

*Author to whom correspondence should be addressed.

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Abstract

Nephrotic syndrome is a illness caused by idiopathic diseases like minimal change nephrotic syndrome and focal segmental glomerulosclerosis, membrane proliferative Glomerulonephritis, membranous Glomerulonephritis and is characterized by increased permeability across the glomerular filtration barrier. Nephrotic syndrome is classified as primary nephrotic syndrome secondary nephrotic syndrome, congenital nephrotic syndrome, and infantile nephrotic syndrome. Nephrotic syndrome consisting of four clinical features like nephrotic range proteinuria edema hyperlipidemia, hypoalbuminemia.

The main cause of nephrotic syndrome are diseases associated with drugs, neoplasia, and rarely genetic disorders. nephrotic syndrome is a chronic relapsing disease for most of steroid response drugs for treatment of nephrotic syndrome corticosteroids not so with immunosuppressive agents people will dependent on corticosteroid remission and some are corticosteroid resistant disease with poor renal prognosis. Using drugs to treat nephrotic syndrome, several complications are improper growth, metabolism, behaviour in patient.

Keywords: NS, FSGS, MCD, corticosteroids, immunosuppressants

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